Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation

<div>The comparison of mRNA expression and survival between DNMT3A mutation and wild-type AML. (a) The mRNA expression of the DNMT3A gene in AML patients’ bone marrow tissue between DNMT3A with mutations and wild type. (b) Kaplan-Meier survival curves for AML patients stratified by DNMT3A mutation. (c) Kaplan-Meier survival curves for DNMT3A wild-type AML patients with different DNMT3A expression levels. AML: acute myeloid leukemia; OS: overall survival.</div>

BioMed Research International

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Figure 1

Figure 1: Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation 