Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation

<div>The protein-protein interactome (PPI) network and hub genes. (a) PPI network of differentially expressed genes. Red nodes mean upregulated differentially expressed genes, and blue nodes mean downregulated differentially expressed genes. The size of nodes means a combined degree of genes. (b) The PPI network and the GO term analysis of the top 10 hub genes. GO: Gene Ontology.</div>

BioMed Research International

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Figure 4

Figure 4: Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation 