Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation

Figure 5

Module analysis of differentially expressed genes. Seven modules screened from the PPI network by the clusterONE plugin of Cytoscape. The genes of the top 3 modules ranked by value were performed using GO enrichment analysis. Red nodes mean upregulated differentially expressed genes, and blue nodes mean downregulated differentially expressed genes. PPI: protein-protein interaction; GO: Gene Ontology.

(a)

(b)

(b)