Targeted Tumor Therapy with Radiolabeled DNA Intercalator: A Possibility? Preclinical Investigations with ¹⁷⁷Lu-Acridine

Table 2

Variation of radiolabeling yield of ¹⁷⁷Lu-acridine complex with incubation time.

Time (min)	% Radiolabeling yield
15
30
45
60

Radiolabeling studies were carried out by incubating 1.5 mg/mL acridine-DOTA conjugate with ¹⁷⁷Lu at 100°C maintaining the reaction pH at 5. Experiments were done in triplicate.