Research Article

A Comparative Study of 2 Different Segmentation Methods of ADC Histogram for Differentiation Genetic Subtypes in Lower-Grade Diffuse Gliomas

Table 6

Comparison of ADC histogram parameters of the two different ROIs between the IDHmut/1p19q− group and IDHmut/1p19q+ group.

Values (×10-6 mm2/s)IDHmut/1p19q+, IDHmut/1p19q−, Test values value

ADCmean13.048a0.006
ADCmean23.268a0.003
ADCmin11.860a0.071
ADCmin21.941a0.060
P5 ADC12.888a0.008
P5 ADC22.890a0.008
P10 ADC13.150a0.005
P10 ADC23.066a0.006
P25 ADC13.397a0.003
P25 ADC23.329a0.003
P50 ADC13.474a0.002
P50 ADC23.487a0.002
P75 ADC12.862a0.009
P75 ADC23.252a0.003
P90 ADC12.088a0.048
P90 ADC22.786a0.010
P95 ADC11.300a0.201
P95 ADC22.494a0.019
ADCmax10.654a0.517
ADCmax21.681a0.101
ADCmode11158.50 (1093.50, 1329.88)-3.059b0.002
ADCmode21170.50 (1093.50, 1328.25)-3.086b0.002
Skewness1-0.200 (-0.446, 0.912)-2.644b0.007
Skewness2-0.227 (-0.526, 0.183)0.378 (0.231, 0.642)-2.093b<0.001
Kurtosis1-0.342 (-0.518, 1.988)1.191 (0.242, 2.290)-1.930b0.054
Kurtosis2-0.354 (-0.482, 0.080)0.102 (-0.309, 0.328)-3.453b0.037
StDev1288.203 (215.736, 366.088)-0.214b0.828
StDev21.932a0.061
Inhomogenity10.172 (0.155, 0.244)0.197 (0.165, 0.251)-1.142b0.253
Inhomogenity2-0.346a0.731
Range11939.25 (1391.00, 2733.13)-0.381b0.703
Range21.089a0.283
Entropy10.467a0.643
Entropy20.527a0.601

1ROI-1; 2ROI-2; a value; b value.