Safety Assessment of Water-Extract Sericin from Silkworm (Bombyx mori) Cocoons Using Different Model Approaches

Table 8

Hematology examination of rats treated with sericin extract for 90 days.

(a)

Sex	Dose (mg/kg)	HGB (g/L)	RBC (10^12/L)	PLT (10^9/L)	HCT (%)	PT (s)	APTT (S)
Male	1000
	500
	250
	Control
Female	1000
	500
	250
	Control

(b)

Sex	Dose (mg/kg)	WBC (10^9/L)	LYM (%)	NEUT (%)	MONO (%)	EO (%)	BASO (%)
Male	1000
	500
	250
	Control
Female	1000
	500
	250
	Control

Note: The values represent the of 10 rats. HGB: hemoglobin concentration; RBC: red blood cell count; PLT: platelet count; HCT: hematocrit; PT: prothrombin time; APTT: activated partial thromboplastin time; WBC: white blood cell count; LYM: percent of lymphocytes; NEUT: percent of neutrophils; MONO: percent of monocytes; EO: percent of eosinophils; BASO: percent of basophils. The values of the treatment groups did not differ statistically from the control according to one-way ANOVA at .