Overproduction of Glucose Oxidase by Aspergillus tubingensis CTM 507 Randomly Obtained Mutants and Study of Its Insecticidal Activity against Ephestia kuehniella

Figure 5

Histopathological effects of glucose oxidase on E. kuehniella midguts. (a) Section through the midgut epithelium of control larvae not exposed to toxins. (b) Section through the midgut epithelium of E. kuehniella larvae fed with wild strain-containing diet. (c) Section through the midgut epithelium of E. kuehniella larvae fed with U4-containing diet. (d) Section through the midgut epithelium of E. kuehniella larvae fed with U11-containing diet. (e) Section through the midgut epithelium of E. kuehniella larvae fed with U12-containing diet. (f) Section through the midgut epithelium of E. kuehniella larvae fed with U16-containing diet. (g) Section through the midgut epithelium of E. kuehniella larvae fed with U20-containing diet. (h) Section through the midgut epithelium of E. kuehniella larvae fed with U21-containing diet. (a) Regular epithelial cell and well-developed lumen contents. (b–h) Extensive damage of the midgut epithelium. Lu: lumen; Am: apical membrane; Bm: basal membrane; V: vacuole formation. Magnification: 40x.

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