Effects of 12-Week Exercise Program on Enzyme Activity of Serum Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Female Patients with Postmenopausal Osteoporosis: A Randomized Control Study

Table 1

Initial clinical and biochemical characteristics for OP female patients in the exercise group and controls.

	Exercise N = 37	Controls N = 31	value^1
Age (years)	64.27 ± 5.61	64.39 ± 4.50	0.924
BMI	26.00 ± 4.48	25.42 ± 3.59	0.556
25 hydroxy vitamin D (nmol/L)	47.03 ± 17.51	45.61 ± 19.83	0.579^2
Calcium, total (mmol/L)	2.44 ± 0.16	2.46 ± 0.21	0.659
24 hour urinary calcium (mmol/24H)	4.72 ± 4.07	4.61 ± 1.64	0.157^2
Calcium ionized (mmol/L)	1.31 ± 0.26	1.34 ± 0.26	0.743
Phosphate (mmol/L)	1.120.21	1.34 ± 1.23	0.985^2
24 hour urinary Phosphate (mmol/24H)	17.54 ± 7.79	14.32 ± 6.54	0.061^2
Creatinine (µmol/L)	67.39 ± 9.92	72.93 ± 7.69	0.128
Creatinine urine (mmol/24H)	8.96 ± 2.94	9.11 ± 2.10	0.392^2
Creatinine clearance (ml/min)	87.06 ± 13.46	79.72 ± 11.14	0.017
Albumin (g/L)	48.41 ± 5.46	48.11 ± 4.54	0.804
Total protein (g/L)	75.56 ± 7.62	73.34 ± 5.80	0.178
PTH (ng/L)	55.00 ± 30.31	54.17 ± 20.89	0.618^2
FT4 (pmol/L)	14.49 ± 2.98	13.95 ± 3.99	0.319^2
TSH (µIU/L)	2.62 ± 2.03	2.76 ± 1.16	0.162^2
Osteocalcin (ng/ml)	24.14 ± 11.72	27.52 ± 9.43	0.048^2
Diuresis (ml) Ƥ	2050.27 ± 472.80	2170.97 ± 466.15	0.209^2
ALP (U/L)	72.59 ± 30.15	74.71 ± 32.23	0.554^2
T-score L1–L4	−2.65 ± 0.89	−2.84 ± 0.74	0.268^2
T-score neck	−2.59 ± 0.80	−2.42 ± 0.85	0.336^2

¹Data are expressed as mean ± SD. Biochemical data are before treatment. vs. controls. ¹Student’s t-test. ²Mann–Whitney test.