Anticolorectal Cancer Effects of AUCAN: Effects to Suppress Proliferation, Metastasis, and Invasion of Tumor Cells

Figure 3

Effects of AUCAN treatment on the apoptosis of CRC cells by flow cytometry analysis. HCT-116 and RKO cells were, respectively, administrated with DMSO (control), AUCAN-IC20, and AUCAN-50 (HCT-116 cells: 8 μM DMSO, 8 μM AUCAN, and 3.2 μM AUCAN; RKO cells: 5 μM DMSO, 2 μM AUCAN, and 5 μM AUCAN). (a) The flow cytometry detection and (b) the apoptosis rate of HCT-116 cells in the control, IC20, and IC50 groups. (c) The cell cycle of HCT-116 cells in the control, IC20, and IC50 groups. vs. the control group, vs. the control group, and vs. the IC20 group. (d) The flow cytometry detection and (e) the apoptosis rate in the indicated groups. (f) The cell cycle of RKO cells in the control, IC20, and IC50 groups. vs. the IC20 group. All data are shown as the , /group. , , and . IC20: 20% inhibition concentration; IC50: half inhibition concentration; DMSO: dimethyl sulfoxide; 116: HCT-116 cells.

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