Microarray Data Mining and Preliminary Bioinformatics Analysis of Hepatitis D Virus-Associated Hepatocellular Carcinoma

Table 4

Functional and pathway enrichment of module 2 genes.

Category	Term	Count	value	Genes
GOTERM_BP_FAT	Type I interferon signaling pathway	12		BST2, IFI27, IFI6, IFIT1, IRF7, IRF9, ISG15, MX1, MX2, OAS1, OAS2, XAF1
GOTERM_BP_FAT	Defense response to virus	9		BST2, IFIT1, IRF7, IRF9, ISG15, MX1, MX2, OAS1, OAS2
GOTERM_BP_FAT	Negative regulation of viral genome replication	5		BST2, IFIT1, ISG15, MX1, OAS1
GOTERM_CC_FAT	Cytosol	10	0.004	BST2, IFIT1, IRF7, IRF9, ISG15, MX1, MX2, OAS1, OAS2, XAF1
GOTERM_CC_FAT	Mitochondrion	6	0.0067	IFI27, IFI6, MX1, MX2, OAS1, XAF1
GOTERM_CC_FAT	Cytoplasmic part	12	0.0067	BST2, IFI27, IFI6, IFIT1, IRF7, IRF9, ISG15, MX1, MX2, OAS1, OAS2, XAF1
GOTERM_MF_FAT	2-5-Oligoadenylate synthetase activity	2	0.00028	OAS1, OAS2
GOTERM_MF_FAT	Double-stranded RNA binding	2	0.0229	OAS1, OAS2
KEGG_PATHWAY	Hepatitis C	5		IFIT1, IRF7, IRF9, OAS1, OAS2
KEGG_PATHWAY	Measles	5		IRF7, IRF9, MX1, OAS1, OAS2
KEGG_PATHWAY	Influenza A	5		IRF7, IRF9, MX1, OAS1, OAS2