BioMed Research International

Research Article

Microarray Data Mining and Preliminary Bioinformatics Analysis of Hepatitis D Virus-Associated Hepatocellular Carcinoma

Table 5

Functional and pathway enrichment of module 3 genes.
CategoryTermCount valueGenes
GOTERM_BP_FATMitotic cell cycle process16CDC45, CDC6, CDCA5, CDCA8, CENPE, DBF4, ESPL1, KIF18A, MCM10, MCM4, MCM7, ORC6, POLE2, PPP2R5C, SKP2, ZWILCH
GOTERM_BP_FATCell cycle17CDC45, CDC6, CDCA5, CDCA8, CENPE, DBF4, ESPL1, KIF18A, KLHL13, MCM10, MCM4, MCM7, ORC6, POLE2, PPP2R5C, SKP2, ZWILCH
GOTERM_BP_FATG1/S transition of mitotic cell cycle9CDC45, CDC6, DBF4, MCM10, MCM4, MCM7, ORC6, POLE2, SKP2
GOTERM_CC_FATChromosomal part13CDC45, CDCA5, CDCA8, CENPE, CENPH, CENPI, KIF18A, MCM10, MCM7, ORC6, POLE2, PPP2R5C, ZWILCH
GOTERM_CC_FATChromosome, centromeric region8CDCA5, CDCA8, CENPE, CENPH, CENPI, KIF18A, PPP2R5C, ZWILCH
GOTERM_CC_FATIntracellular nonmembrane-bounded organelle18CDC45, CDC6, CDCA5, CDCA8, CENPE, CENPH, CENPI, ESPL1, KCTD6, KIF18A, MCM10, MCM7, ORC6, POLE2, PPP2R5C, RNF213, SKP2, ZWILCH
GOTERM_MF_FATDNA replication origin binding30.00011CDC45, MCM10, ORC6
GOTERM_MF_FATSingle-stranded DNA binding40.00037CDC45, MCM10, MCM4, MCM7
GOTERM_MF_FATDNA helicase activity30.00069CDC45, MCM4, MCM7
KEGG_PATHWAYCell cycle8CDC45, CDC6, DBF4, ESPL1, MCM4, MCM7, ORC6, SKP2
KEGG_PATHWAYDNA replication30.00022MCM4, MCM7, POLE2
KEGG_PATHWAYUbiquitin-mediated proteolysis40.00024KLHL13, SKP2, TCEB1, TRIM37