Microarray Data Mining and Preliminary Bioinformatics Analysis of Hepatitis D Virus-Associated Hepatocellular Carcinoma

Table 6

Univariate and Multivariate Cox proportional hazards model analysis of overall survival of HCC.

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	value	HR	95% CI	value
CDCA8	1.11	1.08-1.15	<0.001	1.10	1.06-1.14	<0.001
Stage I			<0.001			0.019
Stage II	1.43	0.88-2.34	0.151	1.23	0.75-2.02	0.416
Stage IIIA	2.68	1.70-4.21	<0.001	2.11	1.31-3.39	0.002
Stage IIIB	2.87	1.02-8.04	0.045	1.84	0.62-5.44	0.273
CDC45	1.13	1.07-1.19	<0.001
CDC6	1.10	1.05-1.15	<0.001
CDCA5	1.09	1.05-1.13	<0.001
MCM4	1.06	1.04-1.09	<0.001
CENPH	1.18	1.08-1.28	<0.001
MCM7	1.01	1.00-1.01	0.029
Gender (F vs. M)	0.82	0.57-1.16	0.257
Age (years)	1.01	0.99-1.02	0.403

F: female; M: male.