[Retracted] A Diagnostic Scoring System for Distinguishing between Tuberculous and Bacterial Meningitis Based on Clinical and Laboratory Findings
Table 2
Univariate analysis for the comparison of variables between tuberculous meningitis patients and bacterial meningitis patients.
Tuberculous meningitis
Bacterial meningitis
Median (IQR) or (%)
Median (IQR) or (%)
Age (years)
35 (23–51)
141
30 (24–46)
100
0.198
Male (sex)
83 (59%)
141
72 (72%)
100
0.036
Disease course (days)
14 (7–28)
141
3 (1–6)
100
≤0.001
Headache
129 (92%)
141
91 (91%)
100
0.895
Fever
128 (91%)
141
95 (95%)
100
0.220
Nausea
99 (70%)
141
65 (65%)
100
0.393
Vomiting
96 (68%)
141
61 (61%)
100
0.256
Coma before admission
66 (47%)
141
50 (50%)
100
0.626
Psychiatric symptoms
46 (33%)
141
39 (39%)
100
0.308
Seizure
23 (16%)
141
14 (14%)
100
0.624
Meningeal signs
104 (92%)
141
92 (92%)
100
≤0.001
Cranial nerve palsies
19 (14%)
141
3 (3%)
100
0.006
Focal neurological deficit
12 (9%)
141
3 (3%)
100
0.082
Coughing for 2 or more weeks
15 (11%)
141
5 (5%)
100
0.059
Recent loss of weight
19 (14%)
141
0
100
≤0.001
Night sweats
15 (11%)
141
1 (1%)
100
0.003
BMRC TBM grade
0.265
Stage I
11 (8%)
141
6 (6%)
100
Stage II
47 (33%)
141
44 (44%)
100
Stage III
83 (59%)
141
50 (50%)
100
Hemoglobin (g/L)
130 (119–139)
141
135 (123–144)
100
0.108
HCT %
38 (35–39)
141
39 (36–42)
100
0.009
WBC count (109/L)
9 (6–11)
141
17 (13–21)
100
≤0.001
Blood % neutrophils
80 (74–85)
141
88 (81–92)
100
≤0.001
Serum sodium (mmol/L)
131 (125–135)
141
139 (134–142)
100
≤0.001
CSF opening pressure (mm H20)
295 (210–350)
141
272 (203–309)
100
0.321
Clear CSF appearance
120 (85%)
141
27 (27%)
100
≤0.001
CSF total WCC (103/mL)
150 (60–300)
141
1145 (489–3160)
100
≤0.001
CSF % neutrophils
15 (10–30)
141
80 (60–90)
100
≤0.001
CSF protein (g/L)
1.55 (1.12–2.08)
141
1.65 (1.14–2.82)
100
0.102
CSF/blood glucose
0.35 (0.23–0.46)
141
0.29 (0.08–0.39)
100
≤0.001
CSF chloride (mmol/L)
111 (106–118)
141
117 (111–123)
100
≤0.001
IQR: interquartile range; BMRC: British Medical Research Council; TBM: tuberculous meningitis; CSF: cerebrospinal fluid; WBC: white blood cell; WCC: white cell count.
