Prognostic Nomograms for Nonelderly Adults with Gastric Signet Ring Cell Carcinoma

Table 1

Patient demographics and clinical characteristics of gastric signet ring cell carcinoma (GSRC) in training and testing cohort.

Variables	All patients	Training cohort	Testing cohort
Number of patients, (%)	1686 (100)	1180 (70)	506 (30)
Age at diagnose (years)
18-44	401 (23.8)	273 (23.1)	128 (25.3)
45-64	1285 (76.2)	907 (76.9)	378 (74.7)
Race
Black	231 (13.7)	156 (13.2)	75 (14.8)
Other	362 (21.5)	253 (21.5)	109 (21.6)
White	1093 (64.8)	771 (65.3)	322 (63.6)
Sex
Female	807 (47.9)	573 (48.6)	234 (46.2)
Male	879 (52.1)	607 (51.4)	272 (53.8)
Marital status
Married	1119 (66.4)	785 (66.5)	334 (66.0)
Unmarried	567 (33.6)	395 (33.5)	172 (34.0)
Primary site
Proximal third (cardia and fundus)	290 (17.2)	206 (17.4)	84 (16.6)
Mid third (body and lesser curvature)	422 (25.0)	303 (25.7)	119 (23.5)
Distal third (antrum and pylorus)	561 (33.3)	383 (32.5)	178 (35.2)
Greater curvature	101 (6.0)	73 (6.2)	28 (5.5)
Overlapping lesions	184 (10.9)	130 (11.0)	54 (10.7)
NOS	128 (7.6)	85 (7.2)	43 (8.5)
Grade
Moderately differentiated (II)	37 (2.2)	25 (2.1)	12 (2.4)
Poorly differentiated (III)	1579 (93.7)	1104 (93.6)	475 (93.9)
Undifferentiated (IV)	70 (4.1)	51 (4.3)	19 (3.7)
T stage
T1	276 (16.4)	182 (15.5)	94 (18.6)
T2	163 (9.7)	109 (9.2)	54 (10.7)
T3	582 (34.5)	426 (36.1)	156 (30.8)
T4	665 (39.4)	463 (39.2)	202 (39.9)
N stage
N0	486 (28.8)	322 (27.3)	164 (32.4)
N1	298 (17.7)	213 (18.1)	85 (16.8)
N2	341 (20.2)	248 (21.0)	93 (18.4)
N3	561 (33.3)	397 (33.6)	164 (32.4)
M stage
M0	1436 (85.2)	1005 (85.2)	431 (85.2)
M1	250 (14.8)	175 (14.8)	75 (14.8)
Tumor size (cm)
≤5	935 (55.5)	651 (55.2)	284 (56.1)
>5	751 (44.5)	529 (44.8)	222 (43.9)
PLNE
<15	1439 (85.3)	1001 (84.8)	438 (86.6)
≥15	247 (14.7)	179 (15.2)	68 (13.4)
Radiation
Yes	725 (43.0)	513 (43.5)	212 (41.9)
No/unknown	961 (57.0)	667 (56.5)	294 (58.1)
Chemotherapy
Yes	1189 (70.5)	837 (70.9)	352 (69.6)
No/unknown	497 (29.5)	343 (29.1)	154 (30.4)