Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-<i>κ</i>B Signal Transduction Pathways in Colon Cancer Cells

<div>Proapoptotic effect of AP in SW480 cell lines. The percentages of annexin-V and annexin-V/PI double-positive in flow cytometry results implicate significantly increased apoptosis in the treated of SW480 cells with AP (10 <i>μ</i>M) as compared to untreated control cells.</div>

BioMed Research International

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Figure 2

Figure 2: Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-<i>κ</i>B Signal Transduction Pathways in Colon Cancer Cells 

Figure 2 | Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-κB Signal Transduction Pathways in Colon Cancer Cells 