Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-<i>κ</i>B Signal Transduction Pathways in Colon Cancer Cells

<div>Schematic representation of the possible mechanism of the SP/NK1R system and aprepitant in CRC-derived SW480 cells. (a) A model of signaling of the SP/NK1R system in the absence of aprepitant. (b) A model of signaling of the SP/NK1R system in exposure to aprepitant.</div>

BioMed Research International

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Figure 6

Figure 6: Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-<i>κ</i>B Signal Transduction Pathways in Colon Cancer Cells 

Figure 6 | Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-κB Signal Transduction Pathways in Colon Cancer Cells 