Review Article

Pharmacologic Activities of Plant-Derived Natural Products on Respiratory Diseases and Inflammations

Table 1

Traditionally used plants in different countries and localities against respiratory disorder.

S.N.Plant names (local name if available)Country (locality if available)Plant parts usedFormsMode of applicationTraditional useReferences

1.Abies pindrowPakistan (Kashmir)BarkPowderInternalCough, chronic asthma[40]
2.Abies pindrow (partal)Pakistan (Kashmir)RootDecoctionInternalCough, bronchitis[40]
3.Abrus precatorius (omisinmisin)Nigeria (Osun State)LeavesDecoctionOralAsthma bronchitis, cough, tuberculosis[42]
4.Acalypha indicaMyanmar (Mon)Whole plantJuiceOralAsthma[43]
5.Acanthus pubescens (Amatojo)UgandaRootBoiledOralCough[44]
6.Achyranthes aspera (Puthkanda)Pakistan(Gujranwala)LeavesDecoctionOralPneumonia[45]
7.Achyranthes aspera (Puthkanda)Pakistan (Soan Valley)RootDecoction, juiceOralPneumonia[46]
8.Aconitum ferox (Seto bikhma)NepalRootDried root juiceOralCough[47]
9.Aconitum heterophyllumNepal (Rasuwa)RootPowderOralCough[48]
10.Aconitum heterophyllumPakistan (Dawarian Village)RootBoiledInternalFlu cough[49]
11.Acorus calamus (Bojho)NepalRootJuice small pieceOrallyBronchitis, to clear the throat and open the voice[41]
12.Adiantum capillus-veneris (Hansraj, Sraj fern)Pakistan (Kashmir)LeavesDecoctionExternalCough, asthma[40]
13.Adiantum capillus-veneris (Khati booti)Pakistan (Soan Valley, Salt Range)Whole partsTeaOralCoughs, bronchitis, and pneumonia[46]
14.Adiantum capillus-venerisPakistan (Dawarian Village)FruitRaw fruitInternalCough[49]
15.Aegle marmelos (Bilpatre, Bael)India (Shimoga)LeavesBoiledOralAsthma[18]
16.Aerva javanica var. javanica (Boo)PakistanInflorescenceDecoctionInternalAsthma[17]
17.Albizia lebbeck Benth (Sharin)Pakistan (Gujranwala)FlowersDecoctionOralAsthma[45]
18.Alhagi maurorum (Puthkanda)Pakistan (Punjab)Whole partsDecoction, juice, infusionOralAsthma[50]
19.Alhagi maurorum (Puthkanda)Pakistan (Punjab)Flowers, leaves, seed, fruit, and stemDecoction, juice, infusion, powder, vegetable, paste, poultice, and teaTopical, oralAsthma, cough[51]
20.Allium cepaPakistan (Punjab)Stem, leavesDecoction, infusion, paste, and juiceOralCough[51]
21.Allium cepaPakistan (Punjab)Stem, leavesDecoction, juiceInternalCough[50]
22.Allium fasciculatum (Rendle Faran, Farun, Chyapi)Nepal (Rasuwa)Whole plantPasteOralSore throat[48]
23.Allium hypsitum (Sternb. Chyapi, Ban Lasun, Jimbu, Jimbu jhar)Nepal (Rasuwa)Whole plantPowderOralCough[48]
24.Allium sativum (Lahsan)Pakistan (Punjab)Stem, leavesDecoction, infusion, paste, tea, and juiceOralAsthma[51]
25.Allium sativum (Thoom)Pakistan (Gujranwala)BulbJuiceOralRespiratory tract infection[45]
26.Alysicarpus vaginalisMyanmar (Mon)Whole plantJuiceOralAsthma and cough[43]
27.Amaranthus albus (Soor, Booti)Pakistan (Punjab)Flowers, leaves, seed, and stemDecoction, juice, infusion, and poulticeTopicalAsthma[51]
28.Amaranthus albus (Soor Booti)Pakistan (Punjab)Whole plantDecoction, juiceInternalPneumonia[50]
29.Anethum graveolensPakistan (Kashmir)FruitPowderedInternalCough and asthma[49]
30.Annas cosmasFruitRaw plantOralAsthma[52]
31.Artemisia indica (Tite pati)NepalLeavesJuiceOralBronchitis[41]
32.Asphodelus tenuifolius Cav (Piyazi)Pakistan (Punjab)Leaves, stemJuice, infusion, powderInternalCough[50]
33.Astilbe rivularis (Thulo ausadhi)Nepal (Rasuwa)RootPowderOralCough[53]
34.Avena sativa (Jai)Pakistan (Punjab)Whole partsPowderedOralCough[50]
35.Averrhoa carambolaNepalFruitPowder, boil with water or milkOralAgainst COVID-19 virus[54]
36.Azadirachta indica (Niimu)UgandaLeavesJuiceOralCough[44]
37.Bergenia ciliata
(Sternb. Pakhanbed)
NepalRhizomeRoot powderOralCough, tonsillitis[47]
38.Bergenia ciliate Haw. (Zakhm-e-Hayat)Pakistan (Kashmir)RootJuiceInternalCough and cold[40]
39.Bistorta amplexicaulis (Masloon)PakistanLeaves and rootsPowderOralRespiratory disorders[55]
40.Bombax ceiba (Simal)NepalRootDecoctionOralBronchitis[41]
41.Bothriocline longipes (Ekyoganyanja)UgandaLeavesJuiceOralCough[44]
42.Callistemon citrinus (Curtis, Skeels)UgandaLeavesBoiled juiceOralCough[44]
43.Calotropis giganteaIndiaRoot and leavesDecoctionOralShortness of breath[56]
44.Calotropis gigantea (Aank)NepalRoot, milky latex, and flowersPasteOralCough, bronchitis[41]
45.Capparis zeylanica (Kurutigana, Soppu)India (Shimoga)LeavesJuiceOralCough[18]
46.Cardia myxa (Lasoora)Pakistan (Punjab)Fruit, stem, leaves, and barkDecoction, juice, vegetable, infusion, and powderOralRespiratory tract infection[51]
47.Cardiospermum halicacabum (Bekkina Budde gida)India (Shimoga)LeavesSmokeInhaleCough[18]
48.Carica papayaLeavesJuiceOralAsthma[52]
49.Carissa carandas (Kavali)India (Shimoga)RootJuiceOralAsthma[18]
50.Carum carvi (Bhote jeera, Sim jeera)Nepal (Rasuwa)Fruit, whole plantFruitsOralCough[48]
51.Cassiope fastigiata (Maudhupi)Nepal (Rasuwa)LeavesLeaves infusionOralCough[48]
52.Castanea sativa (chestnut)Pakistan (Kashmir)LeavesDecoctionInternalSore throat[40]
53.Centella asiatica (Kutukumwe)UgandaLeavesJuiceOralCough[44]
54.Chenopodium album (Lullar)PakistanFruitPowderedInternalAsthma, whooping cough[17]
55.Chromolaena odorataMyanmar (Mon)Whole plantJuiceOralCough[43]
56.Chrysanthemum indicum (Gul-e-Daudi)Pakistan (Punjab)Flowers, leaves, and stemDecoction, juice, and powderedInternalCough[50]
57.Clematis gouriana (Ballivadaka, Gourian clematis)India (Shimoga)FlowersPowderOralAsthma[18]
58.Clematis montana (Langi)Pakistan (Kashmir)FlowersDecoctedInternalCough[40]
59.Coccinia grandis (Voigt Golkakri)NepalRootRoot extractOralPneumonia, tonsillitis, and throat infection[47]
60.Conyza bonariensis (Choozni)Pakistan (Punjab)Leaves, stemPowdered, juice, and infusionInternalCough[50]
61.Coriandrum sativum (Dhaniya)Pakistan (Punjab)Whole partsDecoction and vegetableOralRespiratory tract infection[51]
62.Coriandrum sativumPakistan (Chitral)Fresh leaves and dried fruitsDecoctionInternalBronchitis[57]
63.Cressa cretica (Bukkan)PakistanWhole plantDecoctionInternalAsthma[17]
64.Cymbopogon citratis (Pire ghans)NepalLeavesTeaOralCough[41]
65.Cymbopogon jwarancusa (Nadak)PakistanWhole plantDecoctionInternalCough, bronchitis[17]
66.Delphinium himalayae (Bhongmar)Nepal (Rasuwa)RootExtractOralCough[53]
67.Dicarnopteris linearis (Muikandochla)India (Tripura)FrondsDecoctionOralThroat pain[58]
68.Dicliptera bupleuroides (Kirch, somni)Pakistan (Kashmir)LeavesDecoctionExternalTreatment of cough[40]
69.Elaeagnus angustifoliaPakistan (Kashmir)FruitRaw fruitInternalCough and cold[40]
70.Elaeagnus angustifoliaPakistan (Kashmir)Ripe fruitsBoiledInternalSore throat[40]
71.Elaeagnus umbellate (Russian Olive)Pakistan (Kashmir)LeavesDecoctionInternalCough[40]
72.Embelia ribes (Vayuvilanga)India (Shimoga)RootJuiceOralCough[18]
73.Enicostemma hyssopifoliumPakistanWhole plantDecoctionInternalCough[17]
74.Eucalyptus grandis (Karutusi)UgandaLeavesBoiled JuiceOralCough[44]
75.Euphorbia heliscopia (Dhodak)Pakistan (Punjab)Whole partsDecoction, juice, infusionOralCough[50]
76.Euphorbia hirta (Kippo)PakistanWhole plantDecoctionInternalAsthma[17]
77.Euphorbia hirta (Dudhi jhar)NepalLeavesDried/soakedOralAgainst COVID-19 virus[54]
78.Euphorbia hirta (Khemychu)India (Tripura)LeavesJuiceGarglingThroat pain[58]
79.Euphorbia prostate (Dhodak)Pakistan (Punjab)Whole partsDecoction, juice, infusionOralCough[50]
80.Gentiana kurroo Royle (Spanthing)Pakistan (Baltistan)FlowersInfusionOralCough[59]
81.Gentianodes tianschanicaPakistan (Baltistan)LeavesInfusionOralPneumonia, bronchitis, cough[59]
82.Glycyrrhiza glabra (Jhestamadhu)India (Shimoga)RootPowderOralAsthma[18]
83.Helianthus annus (Suraj Makhi)Pakistan (Punjab)Whole plantPowder, paste, ashInternalRespiratory tract infection[50]
84.Helichrysum schimperi (Moeser, Ekyeeza)UgandaLeavesPowderOralPneumonia[44]
85.Hydrocotyl verdicilltaMyanmar (Mon)Whole plantDecoctionOralAsthma[43]
86.Justica adhatoda (Vahaekar)Pakistan (Soan Valley)Leaves and rootsJuiceOral with gingerCough[46]
87.Justicia adhatoda (Baykr)Pakistan (Gujranwala)Leaves and flowersDecoctionOralCough[45]
88.Justicia adhatoda (Asuamfang)India (Tripura)Root, leavesDecoction, juiceOralPneumonia and cough[58]
89.Justicia adhatodaIndia (Shimoga)RootRoot paste with human breast milkOralBronchitis[18]
90.Lantana camara (Lantani)Pakistan (Punjab)Leaves, stemJuice, infusion, powderInternal (oral)Asthma[50]
91.Malva parviflora (Sunchal)Pakistan (Gujranwala)LeavesDecoctionOralCough[45]
92.Malva parviflora (Ekituruguma)UgandaLeavesPowderOralPneumonia[44]
93.Mangifera indica (L. Omuyembe)UgandaBarkBoiledOralCough[44]
94.Mentha riyleana (Podina)Pakistan (Kashmir)LeavesJuiceInternalCough[40]
95.Mentha spicata (Podina)Pakistan (Sudhanoti)Leaves, rootPasteOralCough, throat pain[60]
96.Mimosa pudica (Hta Muck)Myanmar (Mon)Whole plantJuiceOralCough[43]
97.Mondia whitei (Hook. F, Skeels, Omurondo)UgandaRootPowderChew orallyCough[44]
98.Morus albaPakistan (Dawarian Village)LeavesBoiledInternalSore throat[49]
99.Morus alba (Cheeta Toot)Pakistan (Sudhanoti)Flowers, rootPasteOral brushCough[60]
100.Morus albaKoreaRoot barkPasteOralCough, bronchitis, and asthma[39]
101.Morus nigraPakistan (Dawarian Village)Fruit pulpSyrupInternalSore throat[49]
102.Morus nigra (Kala too)Pakistan (Gujranwala)FruitJuiceOralSore throat, cough[45]
103.Nepeta erecta (Boyle ex Benth Berth Mominan)Pakistan (Baltistan)LeavesInfusionOralCough[59]
104.Nepeta erecta Royle ex.Pakistan (Kashmir)FlowersJuiceInternalCough[40]
105.Ocimum suave Wild., (Omujaaja)UgandaLeavesBoiled JuiceOralCough[44]
106.Ocimum tenuiflorum (Krishna Tulsi)NepalWhole plantDecoctionOralCough[41]
107.Onosma bracteatum WallPakistan (Dawarian Village)RootPowderedInternalAsthma and bronchitis[49]
108.Otthochloa compressa (Nooli)Pakistan (Punjab)Leaves, stemDecoction, juice, teaOralCough[50]
109.Oxalis debilis (Teenpatra)PakistanLeavesPowderOralAsthma[55]
110.Paris polyphylla Sm. (Satuwa)NepalRootPowder juiceOralCough[47]
111.Persea Americana (Ovacado)UgandaLeavesBoiled juiceOralCough[44]
112.Phalaris minor (Dumbi sitt)Pakistan (Punjab)Stem, leavesInfusion, pasteOralCough[51]
113.Phyllanthus emblica (Amala)NepalBark and fruitJuiceOralShore throat[41]
114.Piper longum (Pipla)NepalFruitFruitsOralCough[47]
115.Pisum sativum (Mattr)Pakistan (Punjab)Whole partsDecoction, juice, infusionOralAsthma[50]
116.Plantago palmata (Embatabata)UgandaLeavesPowderOralPneumonia[44]
117.Plectranthus barbatus (Ekicuncu)UgandaLeavesJuiceOralCough[44]
118.Populus tremula (Peepal)Pakistan (Punjab)Leaves, barkDecoction, juice, and infusionOralCough[51]
119.Portulaca quadrifida (Dasi kulfa)Pakistan (Gujranwala)LeavesInfusionOralRespiratory problems[45]
120.Prunus persica Linn (Aru)Pakistan (Kashmir)LeavesJuiceInternalCough, bronchitis. [40]
121.Punica granatum (Druna)Pakistan (Kashmir)FruitRaw fruitInternalCough[40]
122.Punica granatumPakistan (Chitral)Fruit rindRaw fruitInternalWhooping cough[57]
123.Quercus baloot (Rein, Shah Baloot, Oak)Pakistan (Kashmir)BarkPowderInternalAsthma[40]
124.Quercus incana (Rein, Ban, Rinji)Pakistan (Kashmir)BarkPowderInternalAsthma, cough[40]
125.Ranunculus muricatusPakistan (Kashmir)Aerial partsCookedInternalAsthma[40]
126.Rheum acuminatum (Thomson Khokim)NepalRhizomeRhizomeOralCough[47]
127.Rhodiola imbricata (Edgew Chundol)Pakistan (Baltistan)RootPowderOralCough[59]
128.Rhoicissus tridentata (Drumm., Omumara)UgandaLeavesBoiled juiceOralCough[44]
129.Rhus vulgaris Meikle (Omukanja)UgandaFruitRaw fruitOralCough[44]
130.Rubia cordifolia (Akaramata)UgandaLeavesJuiceOralPneumonia[44]
131.Rumex chalepensis (Khar palak)Pakistan (Punjab)Leaves, stemDecoction, juice, teaOralCough[50]
132.Rumex dentatus (Khar palak)Pakistan (Punjab)Leaves, stemDecoction, juice, teaOralCough[50]
133.Rumex hastatus (Khatimal)Pakistan (Kashmir)RootJuiceInternalCough, asthma[40]
134.Saccharum officinarumNigeria (Osun State)StemMacerationOralAsthma, respiratory diseases in children[42]
135.Salsola baryosma (Khaar)Pakistan (Punjab)Stem, leavesDecoction, infusion, and juiceOralCough[51]
136.Salvia hiansPakistan (Kashmir)LeavesJuiceInternalCough[40]
137.Senegalia rugata Lam.Myanmar (Mon)Leaves/whole plantDecoctionOralAsthma[43]
138.Solanecio cydoniifolius (Eirarira)UgandaRootBoiledOralCough[44]
139.Solanum surattense (Mookri)Pakistan (Gujranwala)RootTeaOralAsthma[45]
140.Solanum surratense (Kndyari)Pakistan (Punjab)Whole partsDecoction, juice, infusion, paste, teaInternalRespiratory tract infection[50]
141.Sonchus wightianus (Mulapate)NepalRootRaw rootOralTonsillitis[47]
142.Spinacia oleracea (Palaki)Pakistan (Punjab)LeavesDecoction, juiceInternalCough[50]
143.Swertia chirayita (Karsten Chiraito)NepalWhole plantBoiled juiceOralCough[47]
144.Swertia ciliate GPakistan (Kashmir)Aerial partDecoctionInternalCough[40]
145.Swertia cordata (G. Don, Clarke Karfo sman)Pakistan (Baltistan)FlowerPowderOral with waterCough[59]
146.Tagetes erecta (Gainda)Pakistan (Punjab)Flowers, leaves, and fruitDecoction, juice, infusion, and powderOralAsthma, respiratory tract infection[51]
147.Tagetes erecta (Gaindi)Pakistan (Punjab)Stem, leaves, and flowersDecoction, powder, pasteTopicalAsthma[50]
148.Taverniera persicaPakistan (Punjab)Fruit, stem, leaves, and seedDecoction, infusion, powder, vegetable, and poulticeOralCough[51]
149.Terminalia bellirica (Barro)NepalStem bark and fruitJuiceOralCough[41]
150.Terminalia chebula (Harro)NepalFruitJuiceOralCough[41]
151.Tetradenia riparia (Omuravunga)UgandaLeavesBoiled juiceOralCough[44]
152.Tinospora sinensis (Sin-don-manwe)Myanmar (Mon)Root/stemDecoctionOralCough[43]
153.Trianthema portulacastrumPakistanLeavesDecoctionInternalAsthma[17]
154.Trianthema portulacastrumPakistan (Gujranwala)RootDecoctionOralAsthma[45]
155.Trianthema triquetra Rottl. (Chulani)Pakistan (Punjab)Flowers, leaves, and stemDecoction, teaOralCough[51]
156.Trichodesma indicum (Handusi booti)Pakistan (Jammu and Kashmir)LeavesBoilingInternalCough[40]
157.Trifolium alexandrium (Berseem)Pakistan (Punjab)Stem, leavesDecoction, juice, vegetable, and pasteOralRespiratory tract infection[51]
158.Tussilago farfara (Churut)Pakistan (Baltistan)LeavesInfusionOralCough, respiratory problems[59]
159.Valeriana hardwickii Wall. (Samayo, Nakali Jatamansi)Nepal (Rasuwa)RootRoot pasteOralCough[48]
160.Valeriana jatamansii (Jones Samayo, Sugandhawal)Nepal (Rasuwa)RootRoot pasteOralCough[48]
161.Verbascum thapsus (Guni puchar)Nepal (Rasuwa)TimberRoot pasteOralAsthma[48]
162.Vernonia amygdalinaNigeria (Osun State)Leaves, stem, barkMacerationOralAsthma, cough, tuberculosis[42]
163.Viburnum grandifloum (Guch)Pakistan (Kashmir)SeedJuiceInternalWhooping cough[40]
164.Viola canescens (Pholala)PakistanLeaves and rootsPasteOralCough and respiratory problems[55]
165.Viola canescens Ex (Banafsa)Pakistan (Kashmir)RootJuiceInternalCough and cold[40]
166.Viola canescensPakistan (Dawarian Village)Leaves and flowersDecoctionInternalBronchitis, respiratory catarrh, coughs, and asthma[49]
167.Viola odorata (Banafshaa)Pakistan (Sudhanoti)Flowers, leaves, rootPasteOral, topicalCough, cure throat infection[60]
168.Vitex negundo (Simali)NepalLeaf juiceJuiceOralCough[41]
169.Vitex trifolia (Kyaung-ban-lay)Myanmar (Mon)BarkDecoctionOralCough/asthma[43]
170.Vitis viniferaPakistan (Dawarian Village)FlowersDecoctionInternal[49]
171.Zanthoxylum armatum (Timur)NepalFruitFruitOralCough[47]
172.Zingiber officinale (Roscoe)UgandaStemJuiceOralCough[44]
173.Zingiber officinale (Aduwa)NepalRhizomeJuiceOralCough[41]