Curcumin Inhibits Replication of Human Parainfluenza Virus Type 3 by Affecting Viral Inclusion Body Formation

Figure 5

Curcumin downregulates cellular PI4KB. MDCK cells (a, b) and A549 cells (c, d) were infected with HPIV3 at an MOI of 0.1; DMSO or curcumin was added after infection. The sham group was nontreated. Cells were collected 36 h after infection, and the HN protein, PI4KB, and β-actin were detected by WB as described in the legend for Figure 1. PI4KB or HN/β-actin for each group was calculated as described in Materials and Methods. Data are from three experiments. Student’s test: ns: nonsignificant; ; .

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