Research Article

[Retracted] Efficacy of Aidi Injection and Brucea javanica Oil Emulsion Injection in Rectal Cancer during CapeOX Adjuvant Chemotherapy

Table 3

Drug-related adverse reactions in the three groups.

Grade 0 (%)Grade 1 + grade 2 (%)Grade 3 + grade 4 (%) value
ADI groupBJOEI groupControl groupADI groupBJOEI groupControl groupADI groupBJOEI groupControl group

Leukopenia70 (87.50)61 (76.25)50 (62.50)8 (10.00)15 (18.75)27 (33.75)2 (2.50)4 (5.00)3 (3.75)12.6450.002
Anemia46 (57.50)39 (48.75)36 (45.00)33 (41.25)39 (48.75)44 (55.00)1 (1.25)2 (2.50)0 (0.00)2.4070.300
Thrombocytopenia77 (96.25)70 (87.50)65 (81.25)3 (3.75)10 (12.50)14 (17.50)0 (0.00)0 (0.00)1 (1.25)8.8600.012
Nausea44 (55.00)59 (73.75)39 (48.75)35 (43.75)20 (25.00)39 (48.75)1 (1.25)1 (1.25)2 (2.50)11.0230.004
Vomiting69 (86.25)70 (87.50)64 (80.00)11 (13.75)10 (12.50)14 (17.50)0 (0.00)0 (0.00)2 (2.50)2.1570.340
Diarrhea54 (67.50)46 (57.50)42 (52.50)25 (31.25)34 (42.50)35 (43.75)1 (1.25)0 (0.00)3 (3.75)4.1010.129
Constipation64 (80.00)62 (77.50)55 (68.75)13 (16.25)16 (20.00)25 (31.25)3 (3.75)2 (2.50)0 (0.00)2.4160.299
ALT increase63 (78.75)73 (91.25)66 (82.50)13 (16.25)7 (8.75)12 (15.00)4 (5.00)0 (0.00)2 (2.50)5.2510.072
AST increase67 (83.75)72 (90.00)64 (80.00)12 (15.00)6 (7.50)13 (16.25)1 (1.25)2 (2.50)3 (3.75)3.0430.218
Creatinine increase72 (90.00)68 (85.00)68 (85.00)8 (10.00)12 (15.00)12 (15.00)0 (0.00)0 (0.00)0 (0.00)1.1490.563
Hand-foot syndrome74 (92.50)72 (90.00)58 (72.50)6 (7.50)8 (10.00)21 (26.25)0 (0.00)0 (0.00)1 (1.25)14.9990.001
Peripheral neuropathy70 (87.50)71 (88.75)62 (77.50)10 (12.50)9 (11.25)16 (20.00)0 (0.00)0 (0.00)2 (2.50)4.8980.086