Research Article
The LC-MS/MS-Based Measurement of Isopimaric Acid in Rat Plasma and Application of Pharmacokinetics
Table 2
Matrix effects and extraction recovery for IPA and IS in rat plasma (
).
| Analyte | Spiked concentration (ng/mL) | Absolute matrix effect | Extraction recovery | Mean (%) | RSD (%) | Mean (%) | RSD (%) |
| IPA | 10 | 111.5 | 11.6 | 113.4 | 9.5 | 400 | 119.0 | 7.1 | 103.9 | 4.9 | 2000 | 110.6 | 9.4 | 110.2 | 8.3 |
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