The LC-MS/MS-Based Measurement of Isopimaric Acid in Rat Plasma and Application of Pharmacokinetics

Table 4

Pharmacokinetic parameters of IPA in rats following p.o or i.v. administration.

PK parameters	i.v.	p.o.
	5 (mg/kg)	50 (mg/kg)	100 (mg/kg)	200 (mg/kg)
(ng·mL^-1)
(h)
(ng·mL^-1)	/
2 (h)	/
AUC(0~24)
AUC(0~∞) (ng·h·mL^-1)
CL/F (L·h^-1)
(h)
MRT (h)