[Retracted] Upregulating hsa-miR-128a Increased the Effects of Pembrolizumab on Laryngeal Cancer Cells via the p53 Pathway

Figure 5

The expression of hsa-miR-128a influenced the p53 pathway. The qRT-PCR was used to evaluate the expression levels of representative genes of the p53 pathway. (a) In Hep2 cells, when upregulating hsa-miR-128a, the expression levels of BMI-1 decreased significantly (), and the expression levels of p53 and p16 increased dramatically (, ). (b) In AMC-HN8 laryngeal cancer cells, overexpressing miR-128a caused reduced BMI-1 expression () and higher expression of p53 and p16 (, ).

(a)

(b)