Research Article

Data-Driven Discovery of Molecular Targets for Antibody-Drug Conjugates in Cancer Treatment

Table 2

Comparison of the mean -scores of the selected markers with their HPA-derived quasi -scores.

Target proteinMean -score (SD)Quasi -scoreMean difference (95% CI)

NECTIN4214.4 (86.7)20014.4 (-6.56 to 35.4)0.175
ERBB282.0 (80.1)100-18.0 (-38.1 to 2.2)0.081

Abbreviations: SD: standard deviation; CI: confidence interval. Quasi -scores calculated from the HPA for NECTIN4 and ERBB2 in patients with urothelial carcinoma.