[Retracted] The Conditioned Medium of Lactobacillus rhamnoides GG Regulates Microglia/Macrophage Polarization and Improves Functional Recovery after Spinal Cord Injury in Rats

Figure 5

LGG-CM treatment reduces neuroinflammation in the spinal cord after SCI. (a) Immunohistochemistry and immunofluorescence images of MMPs in the spinal cord at 7 days post-SCI. (b–e) The mRNA levels of iNOS (b), IL-6 (c), IL-1β (d), and TNF-α (e) near the injury section at day 7 post-SCI of the sham operation, SCI+vehicle, and SCI+LGG-CM treatments. (f, g) The mRNA levels of TGF-β1 (f) and CD206 (g) near the injury section at day 7 post-SCI of the sham operation, SCI+vehicle, and SCI+LGG-CM treatments. (h) Upregulation of MMP-9 activity after SCI is demonstrated. After LGG-CM treatment, the activity was downregulated.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)