Inactivated Nevus Tissue with High Hydrostatic Pressure Treatment Used as a Dermal Substitute after a 28-Day Cryopreservation Period

Figure 8

H&E-stained sections of nevus tissues harvested 14 days after implantation in nude mice. Red arrowheads indicate regenerated epidermis. No epidermal regeneration was observed in all six samples in both the fresh without CE and cryopreserved without CE groups. Epidermal regeneration was observed in five of six samples in the fresh with CE group, and in four of six samples in the cryopreserved with CE group (the images of the samples with epidermal generation are surrounded with a red line). CE: cultured epidermis.