Proteome Analysis of the Hypothalamic Arcuate Nucleus in Chronic High-Fat Diet-Induced Obesity

Table 2

GO pathway analysis—cellular component.

Term (GO ID)	Reference	Observed	Expected	F.E.	value	FDR
Small-subunit processome (0032040)	37	5	0.29	17.22
Preribosome (0030684)	81	6	0.64	9.44
Protein-containing complex (0032991)	5312	64	41.69	1.54
Nucleolus (0005730)	808	19	6.34	3
Nuclear lumen (0031981)	3906	60	30.66	1.96
Intracellular organelle lumen (0070013)	4314	64	33.86	1.89
Organelle lumen (0043233)	4315	64	33.87	1.89
Membrane-enclosed lumen (0031974)	4315	64	33.87	1.89
Cellular anatomical entity (0110165)	18664	170	146.49	1.16
Organelle (0043226)	12317	140	96.68	1.45
Intracellular organelle (0043229)	11971	135	93.96	1.44
Intracellular (0005622)	13708	146	107.59	1.36
Nucleus (0005634)	6832	79	53.62	1.47
Intracellular membrane-bounded organelle (0043231)	10296	119	80.81	1.47
Membrane-bounded organelle (0043227)	11045	127	86.69	1.46
Intracellular nonmembrane-bounded organelle (0043232)	4175	55	32.77	1.68
Nonmembrane-bounded organelle (0043228)	4194	55	32.92	1.67
Mitochondrion (GO:0005739)	1798	30	14.11	2.13
Cytoplasm (0005737)	10948	126	85.93	1.47
Cytosol (0005829)	3534	50	27.74	1.8
Nucleoplasm (0005654)	3331	47	26.14	1.8

GO: Gene Ontology; FDR: false discovery rate; F.E.: fold enrichment.