Melatonin Supplementation and Anthropometric Indices: A Randomized Double-Blind Controlled Clinical Trial

Table 3

Mean and standard deviation of the study outcomes.

Outcome	Group	Time			value
		Baseline	6^th week	12^th week
Weight (kg)	Melatonin	^a	^b	^b	0.001^†
	Placebo	^a	^b	^b	0.001^‡
	value	0.35^##	0.28^##	0.24^##
BMI (kg/m^2)	Melatonin	^a	^b	^b	0.001^‡
	Placebo	^a	^b	^b	0.002^‡
	value	0.30^#	0.08^#	0.10^#
Waist circumference (cm)	Melatonin	^a	^b	^c	0.001^†
	Placebo	^a	^b	^b	0.001^‡
	value	0.65^##	0.38^#	0.62^#
Body fat mass (%)	Melatonin	^a	^a,b	^b	0.196^†
	Placebo	^a	^a	^a	0.234^†
	value	0.64^##	0.55^##	0.39^#
Physical activity score (met.h/day)	Melatonin	^a	^a	^a	0.065^†
	Placebo	^a	^b	^b,a	0.128^†
	value	0.54^##	0.14^##	0.93^#
Total daily sleep (hour)	Melatonin	^a	^a	^a	0.229^‡
	Placebo	^a	^a	^a	0.172^†
	value	0.87^#	0.21^##	0.41^#
Nocturnal saliva melatonin (pgr/mL)	Melatonin		—		0.629
	Placebo		—		0.235
	value	0.579^##	—	0.620^##
Diurnal saliva melatonin (pgr/mL)	Melatonin		—		0.286
	Placebo		—		0.841
	value	0.704^##	—	0.737^##
Average saliva melatonin (pgr/mL)	Melatonin		—		0.44
	Placebo		—		0.63
	value	0.63^##	—	0.64^##

^a,b,cThe same letters in two-sided comparisons of a row indicate no significant difference. ^†Nonparametric Friedman test. ^‡Repeated measure ANOVA. ^#Independent sample -test. ^##Nonparametric Mann–Whitney test. Wilcoxon signed ranks test. value less than 0.05 was considered as significant.