Protective Effects of Iridoid Glycoside from Corni Fructus on Type 2 Diabetes with Nonalcoholic Fatty Liver in Mice

Figure 2

Effects of IG on body weight, FBG (fasting blood glucose), OGTT (oral glucose tolerance test), and blood glucose AUC (areas under the curve) in T2DM with NAFLD mice. (a, b) The body weight (a) and FBG (b) of the mice were measured over a four-week observation period. (c) The mice were orally administered with glucose solution at 2 g/kg BW after an overnight fasting, and blood glucose level in tail-vein sample was measured immediately prior (0 min), 30, 60, 120, and 180 min later. (d) The areas under the curve (AUC) from time zero to the last measured time were calculated, and values were expressed as ( for each group). One-way or two-way ANOVA was carried out followed by post hoc Tukey multiple comparison test. ^#, ^##, ^### compared with the NC group; , , compared with the DM group. The data are representative of three experiments.

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