Chemoradiotherapy and Increased Prescription Dose in Esophageal Squamous Cell Cancer: A Retrospective Study
Table 1
Target volume definitions.
NCCN guideline definition#
Modified definition
Prescription dose
GTV
Primary tumor (GTVt) and involved lymph node (GTVnd)
Primary tumor (GTVt) and involved lymph node (GTVnd)
66-68 Gy, 2.0-2.2 Gy/fraction
CTV
3-4 cm expansion above and below the edge of GTVt and 1 cm expansion around the esophageal wall as primary tumor CTV. The nodal GTV plus an expansion of 0.5-1.5 cm as the nodal CTV. Elective nodal regions should be included.
3 cm expansion above and below the edge of the GTVt and 1-2 mm expansion around the esophageal wall as CTV1. Elective nodal regions defined as CTV2 and GTVnd should include in CTV2.
