Formulation, Optimization, In Vitro and In Vivo Evaluation of Saxagliptin-Loaded Lipospheres for an Improved Pharmacokinetic Behavior

Table 3

Results of analysis of variance (ANOVA) for PY, EE, and DR with their corresponding value.

Source	Percentage yield ()		EE ()		DR ()
	value	value; prob > F	value	value	value	value
Model	11.43	0.0032	9.36	0.0038	39.08	<0.0001
BA	25.69	0.0014	11.09	0.0033	38.08	0.0004
T-80	22.82	0.0019	14.48	0.0029	145.04	<0.0001
SS	15.96	0.0026	14.48	0.0029	81.28	<0.0001
	9.03	0.0481	5.07	0.0591	8.61	0.0047
	4.46	0.0580	2.07	0.2712	9.27	0.037
	3.58	0.0253	3.47	0.2982	13.13	0.0017
	5.31	0.0614	8.08	0.0041	5.09	0.0593
	13.07	0.0029	2.39	0.0044	43.65	0.0002
	16.38	0.0021	12.35	0.0092	32.62	0.0006
LOF	217.26	0.0008	182.53	0.0004	55.58	0.0193