Prognostic Factors and a Nomogram Predicting Overall Survival in Patients with Limb Chondrosarcomas: A Population-Based Study
Table 1
Characteristics of patients with limb chondrosarcomas.
Variable
Training group ()
Validation group ()
Total ()
value
Age at diagnosis (years)
0.10
Mean (SD)
50.87 (16.99)
53.02 (17.24)
51.51 (17.08)
Median (Q1, Q3)
51.5 (17.0, 102.5)
45.0 (15.0, 95.0)
51.0 (16.0, 100.0)
Min, max
10.0, 90.0
8.0, 89.0
8.0, 90.0
Age (years)
0.07
<40
145 (25.3%)
55 (22.8%)
200 (24.6%)
40-59
247 (43.2%)
88 (36.5%)
335 (41.2%)
≥60
180 (31.5%)
98 (40.7%)
278 (34.2%)
Race
0.38
White
488 (85.3%)
214 (88.8%)
702 (86.3%)
Black
51 (8.9%)
15 (6.2%)
66 (8.1%)
Other
33 (5.8%)
12 (5.0%)
45 (5.5%)
Sex
Male
319 (55.8%)
133 (55.2%)
452 (55.6%)
0.88
Female
253 (44.2%)
108 (44.8%)
361 (44.4%)
Site
0.27
LU
190 (33.2%)
91 (37.8%)
281 (34.6%)
SU
20 (3.5%)
10 (4.1%)
30 (3.7%)
LL
335 (58.6%)
124 (51.5%)
459 (56.5%)
SL
27 (4.7%)
16 (6.6%)
43 (5.3%)
Histology
0.37
Conventional
470 (82.2%)
198 (82.2%)
668 (82.2%)
Myxoid
24 (4.2%)
15 (6.2%)
39 (4.8%)
Dedifferentiated
78 (13.6%)
28 (11.6%)
106 (13.0%)
Grade
Grade I
202 (35.3%)
91 (37.8%)
293 (36.0%)
0.59
Grade II
223 (39.0%)
95 (39.4%)
318 (39.1%)
Grade III
76 (13.3%)
33 (13.7%)
109 (13.4%)
Grade IV
71 (12.4%)
22 (9.1%)
93 (11.4%)
Laterality
0.52
Left
273 (47.7%)
121 (50.2%)
394 (48.5%)
Right
299 (52.3%)
120 (49.8%)
419 (51.5%)
Stage
0.19
Localized
356 (62.2%)
141 (58.5%)
497 (61.1%)
Regional
168 (29.4%)
85 (35.3%)
253 (31.1%)
Distant
48 (8.4%)
15 (6.2%)
63 (7.7%)
Surgery performed
0.23
No
33 (5.8%)
9 (3.7%)
42 (5.2%)
Yes
539 (94.2%)
232 (96.3%)
771 (94.8%)
Total number of tumors
0.08
526 (92.0%)
230 (95.4%)
756 (93.0%)
46 (8.0%)
11 (4.6%)
57 (7.0%)
Radiation
0.56
No
540 (94.4%)
225 (93.4%)
765 (94.1%)
Yes
32 (5.6%)
16 (6.6%)
48 (5.9%)
Chemotherapy
0.84
No
522 (91.3%)
221 (91.7%)
743 (91.4%)
Yes
50 (8.7%)
20 (8.3%)
70 (8.6%)
Tumor size
0.29
<8 cm
337 (58.9%)
134 (55.6%)
471 (57.9%)
8-13 cm
127 (22.2%)
66 (27.4%)
193 (23.7%)
≥13 cm
108 (18.9%)
41 (17.0%)
149 (18.3%)
Survival time (months)
0.16
Mean (SD)
61.01 (46.37)
56.06 (45.03)
59.54 (46.00)
Median (Q1, Q3)
51.5 (17.0, 102.5)
45.0 (15.0, 95.0)
51.0 (16.0, 100.0)
Min, max
1.0, 154.0
1.0, 155.0
1.0, 155.0
Note: LU: long bones: upper limb, scapula, and associated joints; SU: short bones: upper limb, scapula, and associated joints; LL: long bones of lower limb and associated joints; SL: short bones of lower limb and associated joints.
