Identification of Hub Gene GRIN1 Correlated with Histological Grade and Prognosis of Glioma by Weighted Gene Coexpression Network Analysis

Figure 5

The establishment and visualization of the PPI network and identification of hub genes. (a) A PPI network was constructed by the STRING website; each circle represents a single gene. Genes are linked by line segments that highlight the association among them. (b) Hub genes were identified by CytoHubba based on the MCC algorithm. Red color represents a high level of hub genes, whereas orange color represents medium level and yellow low level of hub genes. (c) Blue nodes represent gene names. Relationships among genes are illustrated by the line connection.

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