Pulsed Electromagnetic Field Affects the Development of Postmenopausal Osteoporotic Women with Vertebral Fractures
Table 4
Effect of pulsed electromagnetic fields (PEMF) on bone microstructure.
Baseline
1 month
3 months
PEMF
Control
value
PEMF
Control
value
PEMF
Control
value
Radius
Total vBMD (g/cm3)
193 (3)
198 (1)
0.81
198 (2)
198 (1)
0.25
203 (2)
193 (2)
0.02
Cortical thickness (mm)
0.43 (0.14)
0.41 (0.13)
0.26
0.49 (0.02)
0.43 (0.03)
0.25
0.54 (0.03)
0.40 (0.02)
0.01
BV/TV (%)
7.26 (0.32)
7.35 (0.22)
0.61
7.29 (0.35)
7.01 (0.23)
0.21
7.33 (0.12)
7.00 (0.53)
0.02
Trabecular.N (mm-1)
1.21 (0.15)
1.23 (0.11)
0.48
1.35 (0.16)
1.30 (0.21)
0.58
1.45 (0.25)
1.31 (0.35)
0.01
Trabecular thickness (mm)
0.072 (0.0003)
0.075 (0.0018)
0.52
0.073 (0.0014)
0.061 (0.0024)
0.04
0.075 (0.0036)
0.063 (0.0025)
0.02
Tibia
Total vBMD (g/cm3)
181 (3)
180 (1)
0.36
161 (2)
150 (3)
0.04
173 (2)
153 (3)
0.02
Cortical thickness (mm)
0.59 (0.052)
0.58 (0.024)
0.52
0.51 (0.021)
0.50 (0.015)
0.58
0.55 (0.034)
0.48 (0.0024)
0.02
BV/TV (%)
9.36 (0.14)
9.56 (0.85)
0.32
9.84 (0.54)
9.25 (0.94)
0.01
9.88 (0.35)
9.02 (0.69)
0.01
Trabecular.N (mm-1)
1.35 (0.03)
1.33 (0.02)
0.48
1.42 (0.01)
1.30 (0.05)
0.25
1.45 (0.05)
1.25 (0.08)
0.01
Trabecular thickness (mm)
0.067 (0.0015)
0.068 (0.0034)
0.28
0.072 (0.0025)
0.061 (0.0025)
0.02
0.075 (0.0021)
0.063 (0.0024)
0.02
PEMF: pulsed electromagnetic field treatment group; BMD: bone mineral density, values derived from mixed-effect models for longitudinal percent change from baseline with a fixed effect for treatment groups, time and adjustments for baseline measurements in an intention-to-treat analysis.
