TDO2 Was Downregulated in Hepatocellular Carcinoma and Inhibited Cell Proliferation by Upregulating the Expression of p21 and p27

Figure 4

(a, b) Flow cytometry analysis showing that overexpression of TDO2 increased the percentage of HepG2 cells in the G1 phase of the cell cycle. (c, d) Flow cytometry analysis showing that overexpression of TDO2 increased the percentage of HLF cells in the G1 phase. (e, f) Overexpression of TDO2 increased the expression of p21 and p27 while decreasing the expression of CDK2 and CDK4 in HepG2 and HLF cells.

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