TDO2 Was Downregulated in Hepatocellular Carcinoma and Inhibited Cell Proliferation by Upregulating the Expression of p21 and p27

Figure 5

(a, b) Macroscopic images of the xenograft tumors comprising HLF and HepG2 line cells stably transfected with a TDO2-overexpression vector or the empty vector control. (c, d) Column chart of the weight of the xenograft tumors comprising HLF or HepG2 cells stably transfected with a TDO2-overexpression vector or the empty vector control. (e, f) Representative photographs of HE staining of the xenograft tumors comprising HLF or HepG2 cells stably transfected with a TDO2-overexpression vector or the empty vector control. (g, h) IHC staining for Ki67 expression in the xenograft tumors comprising HLF or HepG2 line cells stably transfected with a TDO2-overexpression vector or the empty vector control.

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