Comprehensive Profile Analysis of Differentially Expressed circRNAs in Glucose Deprivation-Induced Human Nucleus Pulposus Cell Degeneration

Figure 1

Expression profiles of circRNAs in NP cells during glucose deprivation. (a, b) The box plot showing the distribution of circRNA profiles in 12 samples. After normalization, the distributions of log₂ ratios among 12 samples are nearly the same (s0, s6, s12, and s24 represent that NP cells were incubated under glucose deprivation for 0, 6, 12, and 24 h, respectively). (c) The number of DECs identified after intercomparison at different time points. (d) Hierarchical clustering of all DECs in NP cells after being incubated under glucose deprivation for 0, 6, 12, and 24 h. DECs: differentially expressed circRNAs.

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