Evaluation of the Response of HOS and Saos-2 Osteosarcoma Cell Lines When Exposed to Different Sizes and Concentrations of Silver Nanoparticles

Table 4

Average percentage values and standard deviations for HOS cell proliferation, when subjected to exposure of different concentrations of 7 and 60 nm AgNPs.

(a) BRDU

7 nm	Control	10 ppm	5 ppm	2.5 ppm	1.25 ppm	0.625 ppm	0.3125 ppm
24 h	100.00 (±15.70)	1.17 (±0.86)	9.20 (±2.88)	112.47 (±25.79)	96.11 (±18.95)	82.67 (±10.46)	61.35 (±2.94)
48 h	100.00 (±6.68)	0 (±0.06)	2.44 (±1.23)	72.62 (±12.73)	75.68 (±18.66)	81.46 (±29.14)	80.94 (±31.82)
72 h	100.00 (±8.54)	-0.69 (±0.27)	4.06 (±1.66)	65.82 (±28.57)	39.49 (±11.78)	61.99 (±5.45)	71.47 (±14.23)

(b) Average

60 nm	Control	10 ppm	5 ppm	2.5 ppm	1.25 ppm	0.625 ppm	0.3125 ppm
24 h	100.00 (±15.70)	5.04 (±5.51)	107.67 (±13.20)	112.89 (±5.62)	91.03 (±4.28)	75.78 (±2.56)	89.00 (±8.63)
48 h	100.00 (±6.68)	1.65 (±2.45)	107.91 (±14.10)	97.75 (±16.07)	68.58 (±13.54)	86.65 (±6.10)	115.76 (±23.11)
72 h	100.00 (±8.54)	4.29 (±4.81)	71.43 (±4.17)	52.65 (±16.85)	59.21 (±9.91)	85.10 (±7.20)	92.33 (±24.92)