Evaluation of the Response of HOS and Saos-2 Osteosarcoma Cell Lines When Exposed to Different Sizes and Concentrations of Silver Nanoparticles

Table 5

Average percentage values and standard deviations for Saos-2 cell proliferation, when subjected to exposure of different concentrations of 7 nm and 60 nm AgNPs.

(a) BRDU

7 nm	Control	10 ppm	5 ppm	2.5 ppm	1.25 ppm	0.625 ppm	0.3125 ppm
24 h	100.00 (±6.45)	108.73 (±3.20)	97.73 (±12.41)	94.23 (±5.28)	89.12 (±0.37)	80.88 (±3.92)	101.99 (±4.68)
48 h	100.00 (±6.62)	59.76 (±16.90)	93.42 (±14.61)	95.31 (±8.78)	91.08 (±0.60)	87.58 (±13.32)	99.91 (±21.24)
72 h	100.00 (±7.07)	83.93 (±9.43)	89.84 (±2.81)	89.75 (±5.69)	90.60 (±1.38)	90.89 (±3.83)	97.02 (±6.91)

(b) Average

60 nm	Control	10 ppm	5 ppm	2.5 ppm	1.25 ppm	0.625 ppm	0.3125 ppm
24 h	100.00 (18.91)	102.21 (4.83)	81.25 (21.52)	90.01 (3.52)	83.03 (16.40)	86.82 (21.28)	95.95 (10.43)
48 h	100.00 (6.62)	100.23 (2.60)	99.28 (14.65)	118.66 (2.05)	110.94 (8.61)	108.84 (4.82)	104.26 (6.75)
72 h	100.00 (7.07)	93.12 (11.91)	85.25 (14.54)	91.60 (13.22)	84.21 (0.60)	93.57 (5.98)	104.29 (7.52)