Research Article

Toxicity of Methanolic Extracts of Seeds of Moringa stenopetala, Moringaceae in Rat Embryos and Fetuses

Table 3

In vivo development of rat embryo following treatment with Moringa seed extracts in the day 12 experiment.

Morphological end pointGroups
G-IG-IIG-IIIG-IVG-V

No. of fetus/group4744413946
Yolk saca
Flexiona,b,c
Heart
CND
Hind brain
Mid brain
Fore brain
Otic systema,ba,b
Optic sysa,ba,b
Olfactory systema,ba,b
Branchial barsa,ba,b
Maxillary process
Mandibular processa,b,c,d
Forelimb
Hind limb

Statistical differences between the groups were analyzed by Duncan’s multiple range tests. Results are expressed as . a compared to pair-fed control. b compared to the ad libitum. c compared to M250 mg/kg. d compared to M500 mg/kg. CND: caudal neural tube.