The Relationship between Aeroallergen Sensitization and Chronic Cough in School-Aged Children from General Population
Table 3
Associations of chronic coughing with constitutional and environmental factors.
(a)
Constitutional factors
Chronic coughing
Crude OR (95% CI)
value
aOR (95% CI)
value
Gender
Girl
Ref
Ref
Boy
1.186 (0.735 to 1.914)
0.484
1.159 (0.677 to 1.985)
0.590
Grade of school
Low
Ref
Ref
Medium
0.931 (0.540 to 1.605)
0.797
1.124 (0.626 to 2.018)
0.695
High
0.352 (0.157 to 0.791)
0.011
0.327 (0.126 to 0.849)
0.022
Obesity
No
Ref
Ref
Yes
1.478 (0.572 to 3.822)
0.420
1.700 (0.645 to 4.480)
0.827
Prematurity or low birth weight
No
Ref
Ref
Yes
1.278 (0.640 to 2.554)
0.487
0.993 (0.438 to 2.253)
0.987
Pet owner
No
Ref
Ref
Yes
1.868 (0.741-4.712)
0.185
1.946 (0.684-5.540)
0.212
Remodeling history
No
Ref
Ref
Yes
1.092 (0.489-2.437)
0.830
1.074 (0.470-2.452)
0.866
Asthma
No
Ref
Ref
Yes
5.914 (3.133 to 11.161)
<0.001
4.116 (1.913 to 8.857)
<0.001
Allergic rhinitis
No
Ref
Ref
Yes
1.974 (1.163 to 3.353)
0.012
1.615 (0.904 to 2.886)
0.105
Atopic dermatitis
No
Ref
Ref
Yes
1.610 (0.957 to 2.709)
0.073
1.248 (0.691 to 2.254)
0.463
(b)
Environmental factors
Univariated
Multivariated
Crude OR (95% CI)
value
aOR (95% CI)
value
Exposure to current smoking
No
Ref
Ref
Yes
3.159 (1.360-7.335)
0.007
4.442 (1.831-10.776)
0.001
Exposure to mold
No
Ref
Ref
Yes
1.818 (1.098-3.009)
0.020
1.988 (1.168-3.383)
0.011
aOR: adjusted odds ratio; CI: confidence interval; LBW: low birth weight. Adjusted for gender, school grade, obesity, sensitization to aeroallergen, prematurity, and/or low birth weight. Adjusted for gender, school grade, sensitization to pollen, and current asthma. Numbers in bold indicate significant differences ().