Association Analysis of LEP Signaling Pathway with Type 2 Diabetes Mellitus in Chinese Han Population from South China

Table 3

23SNP genotyping results for 15 genes in the LEP signaling pathway.

Gene	SNP	Allele		Call rate (%)	MAF	HWE
		Minor	Major
LEP	rs4731426	G	C	98.37	0.303	0.161
	rs2167270	A	G	98.34	0.238	0.095
LEPR	rs12405556	G	T	98.34	0.158	1.002
JAK1	rs17127107	C	G	98.32	0.314	0.152
	rs10889502	G	C	98.37	0.340	0.943
JAK2	rs7849191	C	T	98.37	0.369	0.351
STAT3	rs9891119	A	C	98.37	0.445	0.851
SHP-2	rs4767860	G	A	98.24	0.347	0.842
PPARGC1A	rs2970847	T	C	98.37	0.241	0.153
	rs6821591	C	T	98.37	0.328	0.672
PRKAA1	rs249429	C	T	98.37	0.220	0.473
	rs3805486	A	G	98.34	0.234	0.111
PRKAA2	rs1342382	T	A	98.34	0.253	0.332
	rs6588640	A	G	98.37	0.251	0.574
PRKAB2	rs6937	T	C	98.34	0.451	0.421
	rs3766522	A	T	98.37	0.119	0.642
PRKAG1	rs10783299	T	C	98.34	0.474	0.622
PRKAG2	rs5017427	A	G	98.37	0.290	0.563
	rs9648724	G	A	98.29	0.235	0.353
PRKAG3	rs645163	C	T	98.37	0.422	0.902
	rs6436094	A	G	98.37	0.450	0.803
Alpha-MSH	rs6713532	T	C	98.37	0.411	0.056
NPY	rs16147	T	C	98.24	0.362	0.0051