Effects of Subacute Exposure of Dibutyl Phthalate on the Homeostatic Model Assessment, Thyroid Function, and Redox Status in Rats

Table 2

Effects of subacute exposure of dibutyl phthalate on relative organ weights (%) in rats.

	Control	DBP; 10 mg/kg	DBP; 50 mg/kg	DBP 100 mg/kg	(treatment)	(linear)	(quadratic)	(treatment×gender)
Liver	^a	^b	^ab	^ab	0.03	0.04	0.11	0.41
Kidney	^a	^ab	^ab	^b	0.01	<0.01	0.81	0.20
Heart					0.10	0.17	0.63	0.51
Lungs					0.88	0.74	0.78	0.59
Spleen					0.19	0.15	0.47	0.45

Data are presented as . Superscripts ^a-b within the row indicate significant differences (). Two-way ANOVA was used for assessing the effects of treatment and gender. Polynomial contrasts (linear and quadratic) were used to assess monotonic and nonmonotonic responses.