Effects of Subacute Exposure of Dibutyl Phthalate on the Homeostatic Model Assessment, Thyroid Function, and Redox Status in Rats

Table 3

Effects of subacute exposure of dibutyl phthalate on fasting glucose, insulin, and insulin sensitivity indexes in rats.

	Control	DBP; 10 mg/kg	DBP; 50 mg/kg	DBP 100 mg/kg	(treatment)	(linear)	(quadratic)	(treatment×gender)
Fasting glucose (mg/dL)					0.09	0.02	0.28	0.25
Fasting insulin (μU/mL)					0.28	0.38	0.25	0.20
HOMA-IR					0.13	0.05	0.87	0.21
QUICKI					0.30	0.12	0.91	0.22
FGIR (mg/10^-4 U)					0.52	0.26	0.41	0.20

Data are presented as . Two-way ANOVA was used for assessing the effects of treatment and gender. Polynomial contrasts (linear and quadratic) were used to assess monotonic and nonmonotonic responses.