Effects of Subacute Exposure of Dibutyl Phthalate on the Homeostatic Model Assessment, Thyroid Function, and Redox Status in Rats
Table 5
Effects of subacute exposure of dibutyl phthalate on the serum biochemistry in rats.
Control
DBP 10 mg/kg
DBP 50 mg/kg
DBP 100 mg/kg
(treatment)
(linear)
(quadratic)
()
Cholesterol (mg/dL)
0.18
0.88
0.14
0.65
Triglycerides (mg/dL)
0.60
0.75
0.71
0.20
HDL (mg/dL)
0.40
0.15
0.74
0.43
Total protein (g/dL)
0.28
0.09
0.51
0.17
Albumin (g/dL)
0.16
0.89
0.13
0.20
Globulin (g/dL)
0.26
0.08
0.88
0.21
A/G ratio
0.58
0.73
0.22
0.25
BUN (mg/dL)
0.29
0.22
0.27
0.28
Creatinine (mg/dL)
0.77
0.61
0.50
0.33
Uric acid (mg/dL)
0.13
0.12
0.46
0.17
ALT (U/L)
0.49
0.43
0.20
0.83
AST (U/L)
0.48
0.23
0.14
0.81
ALP (U/L)
0.53
0.22
0.35
0.71
LDH (U/L)
0.78
0.51
0.88
0.67
GGT (U/L)
0.74
0.61
0.69
0.43
CK (U/L)
0.06
0.03
0.58
0.19
Data are presented as . Two-way ANOVA was used for assessing the effects of treatment and gender. Polynomial contrasts (linear and quadratic) were used to assess monotonic and nonmonotonic responses.
