Research Article

Based on the Beers Criteria 2019 Edition Over-the-Counter Drugs Risk Confirmation of Elderly Chinese

Table 1

Varieties of OTC drugs containing PIM ingredients.

Indication PIM ingredientNumber of varieties (%)Varieties

Cold medicines34 (47.9)
Chlorpheniramine28 (39.4)Paracetamol and Chlorphenamine maleate with three herb extracts capsules
Paracetamol pseudoephedrine hydrochloride and chlorpheniramine maleate (capsules, chewable tablets, effervescent granules)
Paracetamol, amantadine hydrochloride, Artificial cow-bezoar, and Chlorphenamine maleate granules
Paracetamol, caffeine, Artificial cow-bezoar, and Chlorphenamine maleate (capsules, tablets)
Paracetamol, caffeine, Guaifenesin, and Chlorphenamine maleate solution
Paracetamol, caffeine, and Chlorphenamine tablets
Paracetamol, caffeine, pseudoephedrine hydrochloride, and Chlorphenamine maleate capsules
Composite Benorilate pseudoephedrine tablets
Fēn kā má mǐn jiāonáng
Paracetamol, pseudoephedrine hydrochloride, dextromethorphan hydrobromide, and Chlorphenamine maleate (capsules, tablets)
Compound Paracetamol and dextromethorphan syrup
Paracetamol, amantadine hydrochloride and Chlorphenamine maleate capsules
Compound Paracetamol and Chlorphenamine maleate granules
Compound Paracetamol and amantadine hydrochloride (capsules, granules, tablets)
Compound Paracetamol and Sulfogaiaool Oral Solution
Compound Asiatic Moonseed, Paracetamol, and Chlorphenamine maleate tablets
Compound Paracetamol caffeine and pseudoephedrine hydrochloride capsules
Granulae Zinci Gluconatis ET Ibuprofeni Compositae
Compound Yinqiao and Paracetamol and Chlorphenamine maleate capsules
Líng huáng ān kā mǐn piàn
Psendoephedrine hydrochloride Chlorphenamine maleate and dextromethorphan Hydrobromide solution
Paracetamol pseudoephedrine hydrochloride and Chlorpheniramine maleate granules
Compound honeysuckle stem and aspirin tablets
Diclofenac sodium enteric-coated tablets
Guaifenesin, Pentoxyverine, citrate, and Chlorphenamine maleate tablets
Guaifenesin, dextromethorphan hydrobromide, methylephedrine hydrochloride, and Chlorphenamine maleate syrup
Compound Clorprenaline Hydrochloride tablets
Compound Guaifenesine Pentoxyverine citrate and Chlorphenamine maleate syrup
Clemastine1 (1.4)Paracetamol Pseudophedrine sulfate and Clemastine Fumarate tablets
Ibuprofen3 (4.2)Ibuprofen and pseudoephedrine hydrochloride (tablets, dispersible tablets, granules)
Granulae zinci cluconatis et ibuprofeni compositae
Xīn bù piàn
Dimenhydrinate2 (2.8)Compound guaiacol potassium sulfonate oral solution
Sulfogaiacol, Pentoxyverine, and promethazine granules
Antihistamine drug7 (9.9)
Chlorpheniramine1 (1.4)Chlorpheniramine maleate tablets
Dimenhydrinate2 (2.8)Diphenhydramine hydrochloride and menthol syrup
Diphenhydramine hydrochloride tablets
Promethazine1 (1.4)Promethazine hydrochloride tablets
Cyproheptadine1 (1.4)Cyproheptadine Hydyochloride tablets
Triprolidine1 (1.4)Triprolidine hydrochloride capsules
Dimenhydrinate1 (1.4)Dimenhydrinate (tablets, Buccal tablets)
Digestive system drugs15 (21.1)
A. belladonna12 (16.9)Aluminum Magnesium and Belladonna tablets
Compound Magnesium Trisilicate and sodium bicarbonate tablets
Compound Belladonnate and Aluminium hydroxide (tablets, powder)
Compound Glycyrrhiza, Bismuth, and Magnesium tablets
Compound Aloe and vitamin U tablets
Compound Aluminium hydroxide tablets
Aluminium hydroxide gel
Compound Corydalis tuber and Aluminium hydroxide tablets
Compound Belladonnate and Aluminium hydroxide (tablets, powder)
Medicated Leaven, Rhubarb, Sodium bicarbonate, and Aluminium hydroxide capsules
Vitamin U, Belladonna, and Aluminium (capsules II, capsules, dispersible tablets)
Vitamin U, Aluminium hydroxide, and Magnesium Trisilicate (capsules, tablets, tablets II)
Omeprazole2 (2.8)Omeprazole enteric-coated capsules
Omeprazole magnesium enteric-coated tablets
Hyoscyamine1 (1.4)Raceanisodamine tablets
Antipyretic analgesics and NSAIDs8 (11.3)
Ibuprofen2 (2.8)Ibuprofen (tablets, dispersible tablets, capsules, syrup, Oral solution, Chewables tablets, Effervescent tablets)
Ibuprofen arginine tablets
Diclofenac1 (1.4)Diclofenac potassium tablets
Ketoprofen1 (1.4)Ketoprofen (tablets, capsules)
Naproxen1 (1.4)Naproxen (tablets, capsules, sustained release capsules, sustained release tablets, enteric-coated microgranules capsules)
Diphenhydramine1 (1.4)Ān fēn lā míng piàn
Chlorzoxazone1 (1.4)Compound Chlorzoxazone tablets
Triprolidine1 (1.4)Paracetamol, Triprolidine hydrochloride, and pseudoephedrine hydrochloride tablets
Nervous system medicines1 (1.4)
Scopolamine
Phenobarbital
1 (1.4)Phenobarbital and scopolamine hydrobromide tablets
Chinese patent medicines6 (8.5)
Chlorpheniramine6 (8.5)Wéi C yín qiào kēlì, Wéi C yín qiào piàn
Gǎnmào ān piàn
Hāi kè píng jiāonáng
Hāi tè líng jiāonáng, Hāi tè líng piàn, Hāi tè líng kēlì
Bíyán kāng piàn
Cāng é bíyán piàn

OTC: over-the-counter; PIM: potentially inappropriate medication; NSAIDs: nonsteroidal anti-inflammatory drugs. Some of the drugs were specific to China, and we translated the names of these drugs through Google translation.