Anti-Inflammatory, Antioxidant, Chemical Characterization, and Safety Assessment of Argania spinosa Fruit Shell Extract from South-Western Morocco

Table 7

Effect of AFSEE (125, 250, and 500 mg/kg bw) and diclofenac (25 mg/kg) on carrageenan-induced paw edema in mice.

Treatment		Mean paw (ml) (% inhibition)
		0 h	1 h	2 h	3 h	4 h
Control
Diclofenac (25 mg/kg bw)	Paw volume
	Inhibition	7.69%	14.9%	18.59%	16.67%	17.68%
AFSEE 125 mg/kg bw	Paw volume
	Inhibition	−10.48%	3.94%	9.55%	14.52%	19.45%
AFSEE 250 mg/kg bw	Paw volume
	Inhibition	−3.85%	10.20%	14.67%	14.52%	22.10%
AFSEE 500 mg/kg bw	Paw volume
	Inhibition	−0.96%	10.58%	11.96%	11.29%	21.10%

Each value is represented as (). bw: body weight. Values with different letter superscripts and in the same column are significantly ( compared to the control group) different.