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BioMed Research International
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2021
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Article
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Tab 5
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Review Article
The Safety and Effectiveness of Bevacizumab in the Treatment of Nonsquamous Non-Small-Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials
Table 5
Sensitivity analyses based on various exclusion criteria for neutropenia.
Excluded trial
No. of trials
No. of patients
Experimental group
Control group
RR (95% CI)
value for RR
(%)
value for heterogeneity
Cortot (2020)
7
2733
1392
1341
1.25 [1.12, 1.39]
<0.0001
48
0.07
Fukuda (2019)
7
2857
1481
1376
1.07 [0.85, 1.34]
0.56
74
0.0008
Kitagawa (2019)
7
2789
1446
1341
1.12 [0.88, 1.42]
0.37
78
0.0002
Niho (2012)
7
2720
1382
1338
1.12 [0.81, 1.55]
0.50
76
0.0004
Reck (2009)
7
2241
1172
1069
1.11 [0.82, 1.50]
0.51
78
0.0001
Reck (2010)
7
2240
1171
1069
1.08 [0.80, 1.45]
0.62
76
0.0003
Saito (2019)
7
2671
1389
1282
1.11 [0.88, 1.41]
0.37
78
0.0002
Sandler (2006)
7
2030
1074
956
1.04 [0.81, 1.33]
0.76
71
0.002