[Retracted] In Silico Characterization of Growth Differentiation Factors as Inhibitors of TNF-Alpha and IL-6 in Immune-Mediated Inflammatory Disease Rheumatoid Arthritis

Figure 4

Protein-protein interactions between myostatin and TNF-α. (a) GDF8/TNF-α docked complex in cartoon representation is shown at the top. Myostatin is shown in green while TNF-α is shown in blue. Interacting residues of the GDF8/TNF-α complex are shown in red color stick representation. (b) All interacting residues of GDF8 and TNF-α. Blue color: H-bonds, red color: salt bridges, yellow color: disulfide bonds, orange color: other contacts. Hydrogen bonds are shown with blue lines. The colors of interacting residues are representing properties of amino acids (i.e., blue: positive, red: negative, green: aliphatic, grey: aliphatic, pink: aromatic, orange: Pro/Gly, and yellow: Cyc).