[Retracted] In Silico Characterization of Growth Differentiation Factors as Inhibitors of TNF-Alpha and IL-6 in Immune-Mediated Inflammatory Disease Rheumatoid Arthritis

Figure 5

Protein-protein interactions between myostatin and IL-6. (a) GDF8/IL-6 docked complex in cartoon representation is shown at the top. Myostatin is shown in green, and IL-6 is shown in yellow. Interacting residues of the GDF8/IL-6 complex are shown in red color stick representation. (b) All interacting residues of GDF8 and IL-6. Blue color: H-bonds, red color: salt bridges, yellow color: disulfide bonds, and orange color: nonbonded contacts. Hydrogen bonds are shown with blue lines. The colors of interacting residues are representing properties of amino acids (i.e., blue: positive, red: negative, green: aliphatic, grey: aliphatic, pink: aromatic, orange: Pro/Gly, and yellow: Cyc).