Research Article

Investigation of Hypoglycemic Peptides Derived from Conserved Regions of adMc1 to Reveal Their Antidiabetic Activities

Table 1

The interactions of top ten devised peptides with DPP-IV as the receptor protein.

Sr. no.Peptide-scoreInteracting residues

1MRGID-17.8389Glu206, Tyr547, Arg356, Pro550
2TTVEV-15.8132Glu206, Tyr662, Ser209, Arg669
3LRQQSR-15.7212Glu206, Tyr547, Arg356, Ser209, Arg358
4TVEV-15.0490Glu205, Tyr662, Asn710, His126
5FDECC-14.6527Glu206, Tyr547
6ECCRE-14.3605Tyr547, Tyr662, Tyr666, Pro550, Arg358, Ser209
7MRGIEN-14.3088Glu206, Tyr662
8RCRQ-13.5417Tyr547, Val207
9TTIT-13.5247Glu205, Ser209
10EECR-13.3807Tyr662, Ser209