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BioMed Research International
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2021
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Article
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Tab 1
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Research Article
Investigation of Hypoglycemic Peptides Derived from Conserved Regions of adMc1 to Reveal Their Antidiabetic Activities
Table 1
The interactions of top ten devised peptides with DPP-IV as the receptor protein.
Sr. no.
Peptide
-
score
Interacting residues
1
MRGID
-17.8389
Glu206, Tyr547, Arg356, Pro550
2
TTVEV
-15.8132
Glu206, Tyr662, Ser209, Arg669
3
LRQQSR
-15.7212
Glu206, Tyr547, Arg356, Ser209, Arg358
4
TVEV
-15.0490
Glu205, Tyr662, Asn710, His126
5
FDECC
-14.6527
Glu206, Tyr547
6
ECCRE
-14.3605
Tyr547, Tyr662, Tyr666, Pro550, Arg358, Ser209
7
MRGIEN
-14.3088
Glu206, Tyr662
8
RCRQ
-13.5417
Tyr547, Val207
9
TTIT
-13.5247
Glu205, Ser209
10
EECR
-13.3807
Tyr662, Ser209